Benzamides/pharmacology; Diabetes Mellitus, Type 2/prevention & control; Hypothalamus/drug effects; I-kappa B Kinase/antagonists & inhibitors; Inflammation/prevention & control; Particulate Matter/toxicity; Protein Kinase Inhibitors/pharmacology; Animals; Anti-Inflammatory Agents/pharmacology; Antibodies, Monoclonal/pharmacology; Benzamides/administration & dosage; Blood Glucose/drug effects; Blood Glucose/metabolism; Diabetes Mellitus, Type 2/chemically induced; Diabetes Mellitus, Type 2/enzymology; Diabetes Mellitus, Type 2/genetics; Diabetes Mellitus, Type 2/immunology; Disease Models, Animal; Energy Metabolism/drug effects; Hypothalamus/enzymology; I-kappa B Kinase/genetics; I-kappa B Kinase/metabolism; Inflammation/chemically induced; Inflammation/enzymology; Inflammation/genetics; Inflammation/immunology; Infliximab; Inhalation Exposure/adverse effects; Injections, Intraventricular; Insulin/blood; Insulin Resistance; Interleukin-6/genetics; Interleukin-6/metabolism; Mice; Oxygen Consumption/drug effects; Protein Kinase Inhibitors/administration & dosage; RNA, Messenger/metabolism; Risk Assessment; Thermogenesis/drug effects; Time Factors; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism