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5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone exerts its anticancer and antiangiogenesis effects through regulation of the Akt/mTOR signaling pathway in human lung cancer cells.
Kim, Ki Mo; Heo, Deok Rim; Lee, Jun; Park, Jong-Shik; Baek, Myung-Gi; Yi, Jin-Mu; Kim, Haejin; Bang, Ok-Sun.
Affiliation
  • Kim KM; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Heo DR; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Lee J; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Park JS; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Baek MG; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Yi JM; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Kim H; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea.
  • Bang OS; Korean Medicine (KM)-Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine (KIOM), 1672 Yuseong-daero, Yuseong-gu, Daejeon 305-811, Republic of Korea. Electronic address: osbang@kiom.re.kr.
Chem Biol Interact ; 225: 32-9, 2015 Jan 05.
Article in En | MEDLINE | ID: mdl-25446852
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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Carcinoma, Non-Small-Cell Lung / Flavanones / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Chem Biol Interact Year: 2015 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Carcinoma, Non-Small-Cell Lung / Flavanones / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Chem Biol Interact Year: 2015 Type: Article