Hydroxysafflor yellow A ameliorates lipopolysaccharide-induced acute lung injury in mice via modulating toll-like receptor 4 signaling pathways.

Liu, Ya-Li; Liu, Ya-Juan; Liu, Yang; Li, Xue-Song; Liu, Shuan-Hu; Pan, Yong-Gui; Zhang, Jian; Liu, Qiang; Hao, Ying-Yan

Liu, Ya-Li; Liu, Ya-Juan; Liu, Yang; Li, Xue-Song; Liu, Shuan-Hu; Pan, Yong-Gui; Zhang, Jian; Liu, Qiang; Hao, Ying-Yan.

Int Immunopharmacol ; 23(2): 649-57, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25466274

Subject(s)

Acute Lung Injury/drug therapy; Anti-Inflammatory Agents/therapeutic use; Chalcone/analogs & derivatives; Endotoxins/toxicity; Quinones/therapeutic use; Signal Transduction/drug effects; Toll-Like Receptor 4/metabolism; Acute Lung Injury/chemically induced; Acute Lung Injury/immunology; Acute Lung Injury/pathology; Animals; Anti-Inflammatory Agents/administration & dosage; Anti-Inflammatory Agents/pharmacology; Blotting, Western; Bronchoalveolar Lavage Fluid/chemistry; Chalcone/administration & dosage; Chalcone/pharmacology; Chalcone/therapeutic use; Cytokines/blood; Cytokines/immunology; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Medicine, Chinese Traditional; Mice, Inbred ICR; Molecular Structure; Quinones/administration & dosage; Quinones/pharmacology

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Quinones / Signal Transduction / Chalcone / Endotoxins / Toll-Like Receptor 4 / Acute Lung Injury / Anti-Inflammatory Agents Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Int Immunopharmacol Year: 2014 Type: Article

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