Valeriana officinalis root extract suppresses physical stress by electric shock and psychological stress by nociceptive stimulation-evoked responses by decreasing the ratio of monoamine neurotransmitters to their metabolites.

Jung, Hyo Young; Yoo, Dae Young; Kim, Woosuk; Nam, Sung Min; Kim, Jong Whi; Choi, Jung Hoon; Kwak, Youn-Gil; Yoon, Yeo Sung; Hwang, In Koo

Jung, Hyo Young; Yoo, Dae Young; Kim, Woosuk; Nam, Sung Min; Kim, Jong Whi; Choi, Jung Hoon; Kwak, Youn-Gil; Yoon, Yeo Sung; Hwang, In Koo.

Affiliation

Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, South Korea. vetmed2@snu.ac.kr.

BMC Complement Altern Med ; 14: 476, 2014 Dec 11.

Article in En | MEDLINE | ID: mdl-25495725

Subject(s)

Biogenic Monoamines/metabolism; Brain/drug effects; Neurotransmitter Agents/therapeutic use; Pain/drug therapy; Phytotherapy; Stress, Psychological/drug therapy; Valerian; Amygdala/metabolism; Animals; Brain/metabolism; Corticosterone/blood; Electroshock; Hippocampus/metabolism; Male; Methoxyhydroxyphenylglycol/analogs & derivatives; Methoxyhydroxyphenylglycol/metabolism; Mice; Mice, Inbred ICR; Neurotransmitter Agents/pharmacology; Norepinephrine/metabolism; Pain/metabolism; Plant Extracts/pharmacology; Plant Extracts/therapeutic use; Plant Roots; Serotonin/metabolism; Stress, Physiological/drug effects; Stress, Psychological/metabolism; Swimming

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Pain / Stress, Psychological / Valerian / Brain / Biogenic Monoamines / Neurotransmitter Agents / Phytotherapy Language: En Journal: BMC Complement Altern Med Year: 2014 Type: Article

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