In the mouse, the activation of the hypothalamic-pituitary-adrenal axis by a lipopolysaccharide (endotoxin) is mediated through interleukin-1.

Rivier, C; Chizzonite, R; Vale, W

Rivier, C; Chizzonite, R; Vale, W.

Affiliation

Rivier C; Clayton Foundation Laboratories for Peptide Biology, Salk Institute, La Jolla, California 92037.

Endocrinology ; 125(6): 2800-5, 1989 Dec.

Article in En | MEDLINE | ID: mdl-2555127

Subject(s)

Adrenal Glands/physiology; Endotoxins/pharmacology; Hypothalamus/physiology; Interleukin-1/physiology; Pituitary Gland/physiology; Adrenocorticotropic Hormone/blood; Animals; Drug Interactions; Escherichia coli; Immunization, Passive; Male; Mice; Mice, Inbred BALB C; Receptors, Immunologic/immunology; Receptors, Immunologic/physiology; Receptors, Interleukin-1; Recombinant Proteins/pharmacology; alpha-MSH/pharmacology

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Database: MEDLINE Main subject: Pituitary Gland / Interleukin-1 / Adrenal Glands / Endotoxins / Hypothalamus Language: En Journal: Endocrinology Year: 1989 Type: Article

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Database: MEDLINE Main subject: Pituitary Gland / Interleukin-1 / Adrenal Glands / Endotoxins / Hypothalamus Language: En Journal: Endocrinology Year: 1989 Type: Article