Promising alternative clinical uses of prostaglandin F2α analogs: beyond the eyelashes.
J Am Acad Dermatol
; 72(4): 712-6, 2015 Apr.
Article
in En
| MEDLINE
| ID: mdl-25601618
ABSTRACT
Prostaglandin F2α analogs, commonly prescribed for glaucoma treatment, have been shown to induce side effects such as cutaneous hypertrichosis and hyperpigmentation. Therefore, these medications have theoretic applications in the treatment of alopecia and disorders of hypopigmentation. We reviewed the literature to find original studies assessing the use of prostaglandin F2α analogs in these settings. Studies and reports were analyzed in regards to androgenic alopecia, alopecia areata, chemotherapy-induced alopecia, vitiligo, and hypopigmented scarring. Based on the results of these studies, and consideration of pathophysiologic mechanism, the most promising applications for prostaglandin F2α analogs include androgenic alopecia, chemotherapy-induced alopecia, and alopecia areata concurrently treated with corticosteroids.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Prostaglandins F, Synthetic
/
Cloprostenol
/
Hypopigmentation
/
Alopecia
/
Amides
Type of study:
Observational_studies
Language:
En
Journal:
J Am Acad Dermatol
Year:
2015
Type:
Article