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Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies.
Hu, Tao; Zhou, Xuelin; Wang, Lin; Or, Penelope M Y; Yeung, John H K; Kwan, Yiu Wa; Cho, Chi Hin.
Affiliation
  • Hu T; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: taohu1985@hotmail.com.
  • Zhou X; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Wang L; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Or PM; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Yeung JH; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Kwan YW; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Cho CH; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Chem Biol Interact ; 230: 1-8, 2015 Mar 25.
Article in En | MEDLINE | ID: mdl-25686904
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Microsomes, Liver / Salvia miltiorrhiza / Abietanes / Cytochrome P-450 CYP2C19 / Cytochrome P-450 CYP2C19 Inhibitors Type of study: Prognostic_studies Language: En Journal: Chem Biol Interact Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Microsomes, Liver / Salvia miltiorrhiza / Abietanes / Cytochrome P-450 CYP2C19 / Cytochrome P-450 CYP2C19 Inhibitors Type of study: Prognostic_studies Language: En Journal: Chem Biol Interact Year: 2015 Type: Article