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Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling.
Larena, Maximilian; Holmgren, Jan; Lebens, Michael; Terrinoni, Manuela; Lundgren, Anna.
Affiliation
  • Larena M; University of Gothenburg Vaccine Research Institute (GUVAX), Department of Microbiology and Immunology, University of Gothenburg, 405 30 Sweden.
  • Holmgren J; University of Gothenburg Vaccine Research Institute (GUVAX), Department of Microbiology and Immunology, University of Gothenburg, 405 30 Sweden.
  • Lebens M; University of Gothenburg Vaccine Research Institute (GUVAX), Department of Microbiology and Immunology, University of Gothenburg, 405 30 Sweden.
  • Terrinoni M; University of Gothenburg Vaccine Research Institute (GUVAX), Department of Microbiology and Immunology, University of Gothenburg, 405 30 Sweden.
  • Lundgren A; University of Gothenburg Vaccine Research Institute (GUVAX), Department of Microbiology and Immunology, University of Gothenburg, 405 30 Sweden anna.lundgren@microbio.gu.se.
J Immunol ; 194(8): 3829-39, 2015 Apr 15.
Article in En | MEDLINE | ID: mdl-25786687
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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Adjuvants, Immunologic / Cholera Toxin / Cyclic AMP-Dependent Protein Kinases / Cyclic AMP / Interleukin-1beta / Th17 Cells / Inflammasomes Language: En Journal: J Immunol Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Adjuvants, Immunologic / Cholera Toxin / Cyclic AMP-Dependent Protein Kinases / Cyclic AMP / Interleukin-1beta / Th17 Cells / Inflammasomes Language: En Journal: J Immunol Year: 2015 Type: Article