Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (IV): phenanthroindolizidine alkaloids from Tylophora tanakae leaves.

Nakano, Daisuke; Ishitsuka, Kenji; Ikeda, Mizuki; Tsuchihashi, Ryota; Okawa, Masafumi; Okabe, Hikaru; Tamura, Kazuo; Kinjo, Junei

Nakano, Daisuke; Ishitsuka, Kenji; Ikeda, Mizuki; Tsuchihashi, Ryota; Okawa, Masafumi; Okabe, Hikaru; Tamura, Kazuo; Kinjo, Junei.

Affiliation

Nakano D; Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.

J Nat Med ; 69(3): 397-401, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25840916

Subject(s)

Alkaloids/pharmacology; Antineoplastic Agents, Phytogenic/pharmacology; Leukemia-Lymphoma, Adult T-Cell/drug therapy; Tylophora/chemistry; Alkaloids/isolation & purification; Antineoplastic Agents, Phytogenic/isolation & purification; Cell Line, Tumor; Cell Proliferation/drug effects; Drug Screening Assays, Antitumor; HTLV-I Infections/drug therapy; Humans; Indolizines/isolation & purification; Indolizines/pharmacology; Leukemia-Lymphoma, Adult T-Cell/virology; Phenanthrolines/isolation & purification; Phenanthrolines/pharmacology; Plant Leaves/chemistry; Structure-Activity Relationship; T-Lymphocytes/drug effects

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Full text: 1 Database: MEDLINE Main subject: Leukemia-Lymphoma, Adult T-Cell / Tylophora / Alkaloids / Antineoplastic Agents, Phytogenic Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Language: En Journal: J Nat Med Year: 2015 Type: Article Affiliation country: Japan

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