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Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR-YY1-PGC1α pathway.
Ji, Kunqian; Zheng, Jinfan; Lv, Jingwei; Xu, Jingwen; Ji, Xinbo; Luo, Yue-Bei; Li, Wei; Zhao, Yuying; Yan, Chuanzhu.
Affiliation
  • Ji K; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Zheng J; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Lv J; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Xu J; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Ji X; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Luo YB; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Li W; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Zhao Y; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China.
  • Yan C; Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Brain Science Research Institute, Department of Neurology, Qilu Hospital, Shandong University, Jinan,
Free Radic Biol Med ; 84: 161-170, 2015 Jul.
Article in En | MEDLINE | ID: mdl-25843656
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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / MELAS Syndrome / Muscle, Skeletal / Energy Metabolism / Fibroblast Growth Factors Language: En Journal: Free Radic Biol Med Year: 2015 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / MELAS Syndrome / Muscle, Skeletal / Energy Metabolism / Fibroblast Growth Factors Language: En Journal: Free Radic Biol Med Year: 2015 Type: Article Affiliation country: China