Leucine supplementation improves acquired growth hormone resistance in rats with protein-energy malnutrition.

Gao, Xuejin; Tian, Feng; Wang, Xinying; Zhao, Jie; Wan, Xiao; Zhang, Li; Wu, Chao; Li, Ning; Li, Jieshou

Gao, Xuejin; Tian, Feng; Wang, Xinying; Zhao, Jie; Wan, Xiao; Zhang, Li; Wu, Chao; Li, Ning; Li, Jieshou.

Affiliation

Gao X; Research Institute of General Surgery, Jinling Hospital, Southern Medical University, Guangzhou, Guangdong Province, China.
Tian F; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Wang X; Research Institute of General Surgery, Jinling Hospital, Southern Medical University, Guangzhou, Guangdong Province, China; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Zhao J; Department of Neurosurgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Wan X; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Zhang L; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Wu C; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Li N; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Li J; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.

PLoS One ; 10(4): e0125023, 2015.

Article in En | MEDLINE | ID: mdl-25909895

Subject(s)

Dietary Supplements; Growth Hormone/metabolism; Leucine/administration & dosage; Animals; Disease Models, Animal; Growth Hormone/blood; Insulin-Like Growth Factor Binding Protein 1/blood; Insulin-Like Growth Factor Binding Protein 1/genetics; Insulin-Like Growth Factor Binding Protein 3/blood; Insulin-Like Growth Factor Binding Protein 3/genetics; Insulin-Like Growth Factor I/genetics; Insulin-Like Growth Factor I/metabolism; Liver/metabolism; Male; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Protein-Energy Malnutrition/diet therapy; Protein-Energy Malnutrition/metabolism; Protein-Energy Malnutrition/pathology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Receptors, Somatotropin/genetics; Signal Transduction; TOR Serine-Threonine Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Growth Hormone / Dietary Supplements / Leucine Type of study: Prognostic_studies Language: En Journal: PLoS One Year: 2015 Type: Article Affiliation country: China

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