Different anticancer effects of Saxifragifolin A on estrogen receptor-positive and estrogen receptor-negative breast cancer cells.

Kim, Kyung-Ho; Kim, Ji-Yun; Kwak, Jong-Hwan; Pyo, Suhkneung

Kim, Kyung-Ho; Kim, Ji-Yun; Kwak, Jong-Hwan; Pyo, Suhkneung.

Affiliation

Kim KH; School of Pharmacy, Sungkyunkwan University, Suwon, Kyunggi-do, 440-746, Republic of Korea.
Kim JY; School of Pharmacy, Sungkyunkwan University, Suwon, Kyunggi-do, 440-746, Republic of Korea.
Kwak JH; School of Pharmacy, Sungkyunkwan University, Suwon, Kyunggi-do, 440-746, Republic of Korea.
Pyo S; School of Pharmacy, Sungkyunkwan University, Suwon, Kyunggi-do, 440-746, Republic of Korea.. Electronic address: snpyo@skku.edu.

Phytomedicine ; 22(9): 820-8, 2015 Aug 15.

Article in En | MEDLINE | ID: mdl-26220629

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacology; Apoptosis/drug effects; Cell Survival/drug effects; Estrogen Receptor alpha/metabolism; Saponins/pharmacology; Breast Neoplasms/pathology; Caspases/metabolism; Cell Line, Tumor/drug effects; Humans; MCF-7 Cells/drug effects; Molecular Structure; Reactive Oxygen Species/metabolism

Key words

ER α; MAPK; MCF-7 cell; MDA-MB-231 cell; ROS; Saxifragifolin A

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Full text: 1 Database: MEDLINE Main subject: Saponins / Cell Survival / Apoptosis / Estrogen Receptor alpha / Antineoplastic Agents, Phytogenic Language: En Journal: Phytomedicine Year: 2015 Type: Article

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