P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer.

Netsomboon, Kesinee; Laffleur, Flavia; Bernkop-Schnürch, A

Netsomboon, Kesinee; Laffleur, Flavia; Bernkop-Schnürch, A.

Affiliation

Netsomboon K; a Department of Pharmaceutical Technology , Institute of Pharmacy, University of Innsbruck , Innsbruck , Austria.
Laffleur F; a Department of Pharmaceutical Technology , Institute of Pharmacy, University of Innsbruck , Innsbruck , Austria.
Bernkop-Schnürch A; a Department of Pharmaceutical Technology , Institute of Pharmacy, University of Innsbruck , Innsbruck , Austria.

Drug Dev Ind Pharm ; 42(4): 668-75, 2016.

Article in En | MEDLINE | ID: mdl-26288998

Subject(s)

ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors; Acrylic Resins/chemical synthesis; Acrylic Resins/pharmacology; Cell Survival/drug effects; Rhodamine 123/chemical synthesis; Rhodamine 123/pharmacology; ATP Binding Cassette Transporter, Subfamily B/physiology; Caco-2 Cells; Cell Survival/physiology; Drug Evaluation, Preclinical/methods; Humans

Key words

Caco-2 cell; efflux; poly(acrylic acid); rhodamine 123; transport

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Full text: 1 Database: MEDLINE Main subject: Acrylic Resins / Cell Survival / ATP Binding Cassette Transporter, Subfamily B / Rhodamine 123 Language: En Journal: Drug Dev Ind Pharm Year: 2016 Type: Article Affiliation country: Austria

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