Isoeugenin, a Novel Nitric Oxide Synthase Inhibitor Isolated from the Rhizomes of Imperata cylindrica.

An, Hyo-Jin; Nugroho, Agung; Song, Byong-Min; Park, Hee-Juhn

An, Hyo-Jin; Nugroho, Agung; Song, Byong-Min; Park, Hee-Juhn.

Affiliation

An HJ; Department of Pharmacology, College of Korean Medicine, Sangji University, Wonju 220-702, Korea. hjan@sj.ac.kr.
Nugroho A; Department of Agro-Industrial Technology, Faculty of Agriculture, Lambung Mangkurat University, Indonesia 70712, Indonesia. agung_tin@yahoo.com.
Song BM; Department of Forest Science, College of Life Science and Natural Resources, Sangji University, Wonju 220-702, Korea. bmsong@sangji.ac.kr.
Park HJ; Department of Pharmaceutical Engineering, College of Health Science, Sangji University, Wonju 220-702, Korea. hjpark@sangji.ac.kr.

Molecules ; 20(12): 21336-45, 2015 Dec 01.

Article in En | MEDLINE | ID: mdl-26633331

Subject(s)

Anti-Inflammatory Agents/pharmacology; Chromones/pharmacology; Enzyme Inhibitors/pharmacology; Macrophages/drug effects; Nitric Oxide Synthase Type II/antagonists & inhibitors; Plant Extracts/pharmacology; Poaceae/chemistry; Rhizome/chemistry; Animals; Anti-Inflammatory Agents/isolation & purification; Chromones/chemistry; Cyclooxygenase 2/chemistry; Cytokines/genetics; Enzyme Inhibitors/isolation & purification; Lipopolysaccharides/pharmacology; Macrophages/cytology; Macrophages/metabolism; Mice; Nitric Oxide/metabolism; RAW 264.7 Cells; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

Key words

HPLC; Imperata cylindrica; NO; RAW264.7 macrophages; isoeugenin

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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Chromones / Rhizome / Enzyme Inhibitors / Nitric Oxide Synthase Type II / Poaceae / Macrophages / Anti-Inflammatory Agents Language: En Journal: Molecules Year: 2015 Type: Article

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