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The protective effects of paeonol against epirubicin-induced hepatotoxicity in 4T1-tumor bearing mice via inhibition of the PI3K/Akt/NF-kB pathway.
Wu, Jing; Xue, Xia; Zhang, Bin; Jiang, Wen; Cao, Hongmei; Wang, Rongmei; Sun, Deqing; Guo, Ruichen.
Affiliation
  • Wu J; Department of Pharmacy, The Second Hospital of Shandong University, Jinan, China; Department of Pharmacology, School of Medicine, Shandong University, Jinan, China.
  • Xue X; Department of Pharmacy, The Second Hospital of Shandong University, Jinan, China.
  • Zhang B; Department of Pharmacy, The Second Hospital of Shandong University, Jinan, China.
  • Jiang W; Central Laboratory, The Second Hospital of Shandong University, Jinan, China.
  • Cao H; Department of Out-patient, People' Hospital of Zhangqiu, Jinan, China.
  • Wang R; Department of Pharmacy, The Second Hospital of Shandong University, Jinan, China.
  • Sun D; Department of Pharmacy, The Second Hospital of Shandong University, Jinan, China. Electronic address: sundq0405@126.com.
  • Guo R; Institute of Clinical Pharmacology, Qi Lu Hospital of Shandong University, Jinan, China. Electronic address: grc7636@126.com.
Chem Biol Interact ; 244: 1-8, 2016 Jan 25.
Article in En | MEDLINE | ID: mdl-26646421
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Acetophenones / Epirubicin / Signal Transduction / NF-kappa B / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Chemical and Drug Induced Liver Injury / Mammary Neoplasms, Experimental Language: En Journal: Chem Biol Interact Year: 2016 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Acetophenones / Epirubicin / Signal Transduction / NF-kappa B / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Chemical and Drug Induced Liver Injury / Mammary Neoplasms, Experimental Language: En Journal: Chem Biol Interact Year: 2016 Type: Article Affiliation country: China