Regulation of Acetate Metabolism and Acetyl Co-a Synthetase 1 (ACS1) Expression by Methanol Expression Regulator 1 (Mxr1p) in the Methylotrophic Yeast Pichia pastoris.

Sahu, Umakant; Rangarajan, Pundi N

Sahu, Umakant; Rangarajan, Pundi N.

Affiliation

Sahu U; From the Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India.
Rangarajan PN; From the Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India pnr@biochem.iisc.ernet.in.

J Biol Chem ; 291(7): 3648-57, 2016 Feb 12.

Article in En | MEDLINE | ID: mdl-26663080

Subject(s)

Acetates/metabolism; Coenzyme A Ligases/metabolism; Fungal Proteins/metabolism; Gene Expression Regulation, Fungal; Peptide Elongation Factor 1/metabolism; Pichia/metabolism; Protein Processing, Post-Translational; Active Transport, Cell Nucleus; Amino Acid Substitution; Coenzyme A Ligases/chemistry; Coenzyme A Ligases/genetics; Fungal Proteins/agonists; Fungal Proteins/chemistry; Fungal Proteins/genetics; Gene Deletion; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Peptide Elongation Factor 1/chemistry; Peptide Elongation Factor 1/genetics; Peptide Fragments/chemistry; Peptide Fragments/genetics; Peptide Fragments/metabolism; Phosphorylation; Pichia/cytology; Pichia/enzymology; Pichia/growth & development; Protein Interaction Domains and Motifs; RNA, Fungal/metabolism; RNA, Messenger/metabolism; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Response Elements

Key words

Pichia pastoris; acetate metabolism; acetyl-CoA synthetase; gene regulation; metabolism; promoter; transcription factor; yeast

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Full text: 1 Database: MEDLINE Main subject: Pichia / Fungal Proteins / Gene Expression Regulation, Fungal / Protein Processing, Post-Translational / Coenzyme A Ligases / Peptide Elongation Factor 1 / Acetates Language: En Journal: J Biol Chem Year: 2016 Type: Article Affiliation country: India

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