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Antimicrobial activity of Aspilia latissima (Asteraceae).
Souza, Jeana M E; Chang, Marilene R; Brito, Daniela Z; Farias, Katyuce S; Damasceno-Junior, Geraldo A; Turatti, Izabel C C; Lopes, Norberto P; Santos, Edson A; Carollo, Carlos A.
Affiliation
  • Souza JM; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
  • Chang MR; Laboratório de Pesquisa em Microbiologia, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
  • Brito DZ; Laboratório de Pesquisa em Microbiologia, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
  • Farias KS; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
  • Damasceno-Junior GA; Laboratório de Botânica, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
  • Turatti IC; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Lopes NP; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Santos EA; Coordenação do Curso de Licenciatura em Química, Universidade Tecnológica Federal do Paraná, Apucarana, PR, Brazil.
  • Carollo CA; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Braz J Microbiol ; 46(4): 1103-10, 2015.
Article in En | MEDLINE | ID: mdl-26691468
We evaluated the antimicrobial activity of Aspilia latissima - an abundant plant from the Brazilian Pantanal region - against Candida albicans, Candida parapsilosis, Candida krusei, Candida tropicalis, Pseudomonas aeruginosa, Enterococcus faecalis, Escherichia coli and Staphylococcus aureus. The crude extracts and fractions showed activity in all tested microorganisms. The chloroform fraction of the leaves and roots showed the most antimicrobial activity against S. aureus, with an MIC of 500 µg/mL. This fraction was submitted to bioautographic assays to characterize the activity of the compounds. Two bands from the leaves (L-A and L-B) and three bands from the roots (R-C, R-D and R-E) were bioactive. Within the root-derived bands, the terpene derivatives stigmasterol, kaurenoic acid and kaura-9(11), 16-dien-18-oic acid were identified. Antibiotic activity of A. latissima is reported for the first time.
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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Asteraceae / Anti-Bacterial Agents / Antifungal Agents Country/Region as subject: America do sul / Brasil Language: En Journal: Braz J Microbiol Year: 2015 Type: Article Affiliation country: Brazil
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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Asteraceae / Anti-Bacterial Agents / Antifungal Agents Country/Region as subject: America do sul / Brasil Language: En Journal: Braz J Microbiol Year: 2015 Type: Article Affiliation country: Brazil