The Molecular Engineering of an Anti-Idiotypic Antibody for Pharmacokinetic Analysis of a Fully Human Anti-Infective.

Lim, She Yah; Chan, Conrad E Z; Lisowska, Malgorzata M; Hanson, Brendon J; MacAry, Paul A

Lim, She Yah; Chan, Conrad E Z; Lisowska, Malgorzata M; Hanson, Brendon J; MacAry, Paul A.

Affiliation

Lim SY; Department of Microbiology, National University of Singapore, Singapore, Singapore.
Chan CE; Immunology Program, Centre for Life Sciences, National University of Singapore, Singapore, Singapore.
Lisowska MM; NUS Graduate School for Integrative Sciences and Engineering, Singapore, Singapore.
Hanson BJ; Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore, Singapore.
MacAry PA; Department of Microbiology, National University of Singapore, Singapore, Singapore.

PLoS One ; 10(12): e0145381, 2015.

Article in En | MEDLINE | ID: mdl-26700297

Subject(s)

Antibodies, Anti-Idiotypic/immunology; Antibodies, Monoclonal/pharmacokinetics; Antibodies, Viral/pharmacology; Dengue Virus/immunology; Animals; Antibodies, Anti-Idiotypic/chemistry; Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/immunology; Antibodies, Viral/chemistry; Antibody Affinity; Antibody Specificity; Cell Surface Display Techniques; Chlorocebus aethiops; Drug Evaluation, Preclinical/methods; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin Fab Fragments/immunology; Mice; Vero Cells

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Full text: 1 Database: MEDLINE Main subject: Antibodies, Anti-Idiotypic / Dengue Virus / Antibodies, Monoclonal / Antibodies, Viral Language: En Journal: PLoS One Year: 2015 Type: Article Affiliation country: Singapore

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