Activating frataxin expression by repeat-targeted nucleic acids.

Li, Liande; Matsui, Masayuki; Corey, David R

Li, Liande; Matsui, Masayuki; Corey, David R.

Affiliation

Li L; Departments of Pharmacology and Biochemistry, UT Southwestern Medical Center at Dallas, 6001 Forest Park Road, Dallas, Texas 75390-9041, USA.
Matsui M; Departments of Pharmacology and Biochemistry, UT Southwestern Medical Center at Dallas, 6001 Forest Park Road, Dallas, Texas 75390-9041, USA.
Corey DR; Departments of Pharmacology and Biochemistry, UT Southwestern Medical Center at Dallas, 6001 Forest Park Road, Dallas, Texas 75390-9041, USA.

Nat Commun ; 7: 10606, 2016 Feb 04.

Article in En | MEDLINE | ID: mdl-26842135

Subject(s)

Fibroblasts/drug effects; Friedreich Ataxia/genetics; Iron-Binding Proteins/drug effects; Nucleic Acids/pharmacology; RNA, Messenger/drug effects; RNA/pharmacology; Argonaute Proteins/metabolism; Blotting, Western; Chromatin Immunoprecipitation; Fibroblasts/metabolism; Friedreich Ataxia/metabolism; Gene Expression Regulation; Humans; Immunoprecipitation; Introns; Iron-Binding Proteins/genetics; Iron-Binding Proteins/metabolism; RNA/genetics; RNA, Messenger/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Trinucleotide Repeat Expansion; Frataxin

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Full text: 1 Database: MEDLINE Main subject: RNA / RNA, Messenger / Friedreich Ataxia / Nucleic Acids / Iron-Binding Proteins / Fibroblasts Language: En Journal: Nat Commun Year: 2016 Type: Article Affiliation country: United States

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