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Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor.
Deng, Rong; Bumbaca, Daniela; Pastuskovas, Cinthia V; Boswell, C Andrew; West, David; Cowan, Kyra J; Chiu, Henry; McBride, Jacqueline; Johnson, Clarissa; Xin, Yan; Koeppen, Hartmut; Leabman, Maya; Iyer, Suhasini.
Affiliation
  • Deng R; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Bumbaca D; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Pastuskovas CV; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Boswell CA; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • West D; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Cowan KJ; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Chiu H; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • McBride J; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Johnson C; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Xin Y; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Koeppen H; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Leabman M; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
  • Iyer S; a Genentech Research and Early Development, Genentech, Inc. , South San Francisco , CA , USA.
MAbs ; 8(3): 593-603, 2016.
Article in En | MEDLINE | ID: mdl-26918260
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Full text: 1 Database: MEDLINE Main subject: B7-H1 Antigen / Cell Cycle Checkpoints / Antibodies, Monoclonal / Antibodies, Neoplasm / Neoplasm Proteins / Neoplasms, Experimental Language: En Journal: MAbs Year: 2016 Type: Article Affiliation country: United States
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: B7-H1 Antigen / Cell Cycle Checkpoints / Antibodies, Monoclonal / Antibodies, Neoplasm / Neoplasm Proteins / Neoplasms, Experimental Language: En Journal: MAbs Year: 2016 Type: Article Affiliation country: United States