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Impaired Inactivation of L-Type Ca2+ Current as a Potential Mechanism for Variable Arrhythmogenic Liability of HERG K+ Channel Blocking Drugs.
Kim, Jae Gon; Sung, Dong Jun; Kim, Hyun-ji; Park, Sang Woong; Won, Kyung Jong; Kim, Bokyung; Shin, Ho Chul; Kim, Ki-Suk; Leem, Chae Hun; Zhang, Yin Hua; Cho, Hana; Bae, Young Min.
Affiliation
  • Kim JG; Department of Physiology and the Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, South Korea.
  • Sung DJ; Next-Generation Pharmaceutical Research Center, Korea Institute of Toxicology, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
  • Kim HJ; Division of Sport Science, College of Science and Technology, Konkuk University, Choongju, South Korea.
  • Park SW; Department of Physiology and the Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, South Korea.
  • Won KJ; Department of Physiology, KU Open Innovation Center, Research Institute of Medical Science, Konkuk University School of Medicine, Chungju, South Korea.
  • Kim B; Department of Physiology, KU Open Innovation Center, Research Institute of Medical Science, Konkuk University School of Medicine, Chungju, South Korea.
  • Shin HC; Department of Physiology, KU Open Innovation Center, Research Institute of Medical Science, Konkuk University School of Medicine, Chungju, South Korea.
  • Kim KS; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Konkuk University, Seoul, South Korea.
  • Leem CH; Next-Generation Pharmaceutical Research Center, Korea Institute of Toxicology, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
  • Zhang YH; Human and Environmental Toxicology Program, University of Science and Technology, Daejeon, South Korea.
  • Cho H; Department of Physiology, University of Ulsan College of Medicine, Seoul, South Korea.
  • Bae YM; Department of Physiology, Seoul National University College of Medicine, Seoul, South Korea.
PLoS One ; 11(3): e0149198, 2016.
Article in En | MEDLINE | ID: mdl-26930604
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Full text: 1 Database: MEDLINE Main subject: Action Potentials / Fluoroquinolones / Potassium Channel Blockers / Myocytes, Cardiac / Anti-Arrhythmia Agents Language: En Journal: PLoS One Year: 2016 Type: Article Affiliation country: South Korea
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Full text: 1 Database: MEDLINE Main subject: Action Potentials / Fluoroquinolones / Potassium Channel Blockers / Myocytes, Cardiac / Anti-Arrhythmia Agents Language: En Journal: PLoS One Year: 2016 Type: Article Affiliation country: South Korea