Your browser doesn't support javascript.
loading
Herquline A, produced by Penicillium herquei FKI-7215, exhibits anti-influenza virus properties.
Chiba, Takuya; Asami, Yukihiro; Suga, Takuya; Watanabe, Yoshihiro; Nagai, Takayuki; Momose, Fumitaka; Nonaka, Kenichi; Iwatsuki, Masato; Yamada, Haruki; Omura, Satoshi; Shiomi, Kazuro.
Affiliation
  • Chiba T; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Asami Y; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Suga T; b Kitasato Institute for Life Sciences , Kitasato University , Tokyo , Japan.
  • Watanabe Y; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Nagai T; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Momose F; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Nonaka K; b Kitasato Institute for Life Sciences , Kitasato University , Tokyo , Japan.
  • Iwatsuki M; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Yamada H; b Kitasato Institute for Life Sciences , Kitasato University , Tokyo , Japan.
  • Omura S; a Graduate School of Infection Control Sciences , Kitasato University , Tokyo , Japan.
  • Shiomi K; b Kitasato Institute for Life Sciences , Kitasato University , Tokyo , Japan.
Biosci Biotechnol Biochem ; 81(1): 59-62, 2017 Jan.
Article in En | MEDLINE | ID: mdl-26999706
ABSTRACT
In the course of screening for new anti-influenza virus antibiotics, we isolated herquline A from a culture broth of the fungus, Penicillium herquei FKI-7215. Herquline A inhibited replication of influenza virus A/PR/8/34 strain in a dose-dependent manner without exhibiting cytotoxicity against several human cell lines. It did not inhibit the viral neuraminidase.
Subject(s)
Key words
Search on Google
Add to My VHL
Print
XML
PubMed Links

Database: MEDLINE Main subject: Antiviral Agents / Orthomyxoviridae / Penicillium / Alkaloids Language: En Journal: Biosci Biotechnol Biochem Year: 2017 Type: Article Affiliation country: Japan
Search on Google
Add to My VHL
Print
XML
PubMed Links

Database: MEDLINE Main subject: Antiviral Agents / Orthomyxoviridae / Penicillium / Alkaloids Language: En Journal: Biosci Biotechnol Biochem Year: 2017 Type: Article Affiliation country: Japan