The importance of minipigs in dermal safety assessment: an overview.

Stricker-Krongrad, Alain; Shoemake, Catherine R; Liu, Jason; Brocksmith, Derek; Bouchard, Guy

Stricker-Krongrad, Alain; Shoemake, Catherine R; Liu, Jason; Brocksmith, Derek; Bouchard, Guy.

Affiliation

Stricker-Krongrad A; a Sinclair Research Center , Columbia , MO , USA and.
Shoemake CR; a Sinclair Research Center , Columbia , MO , USA and.
Liu J; a Sinclair Research Center , Columbia , MO , USA and.
Brocksmith D; b Sinclair BioResources , Columbia , MO , USA.
Bouchard G; a Sinclair Research Center , Columbia , MO , USA and.

Cutan Ocul Toxicol ; 36(2): 105-113, 2017 Jun.

Article in En | MEDLINE | ID: mdl-27161161

Subject(s)

Dermatologic Agents/adverse effects; Skin/drug effects; Swine, Miniature; Administration, Cutaneous; Animals; Dermatologic Agents/administration & dosage; Dermatologic Agents/pharmacokinetics; Dermatologic Agents/pharmacology; Drug Design; Drug Evaluation, Preclinical/methods; Humans; Models, Animal; Safety; Skin/pathology; Skin Absorption; Skin Physiological Phenomena/drug effects; Swine; Swine, Miniature/anatomy & histology; Swine, Miniature/physiology; Toxicity Tests; Translational Research, Biomedical/methods

Key words

Dermal drug safety; dermal pharmacology; dermal toxicology

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Full text: 1 Database: MEDLINE Main subject: Skin / Swine, Miniature / Dermatologic Agents Language: En Journal: Cutan Ocul Toxicol Year: 2017 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Skin / Swine, Miniature / Dermatologic Agents Language: En Journal: Cutan Ocul Toxicol Year: 2017 Type: Article