Arachidonic acid metabolomic study of BPH in rats and the interventional effects of Zishen pill, a traditional Chinese medicine.

Bian, Qiaoxia; Wang, Weihui; Wang, Nannan; Peng, Yan; Ma, Wen; Dai, Ronghua

Bian, Qiaoxia; Wang, Weihui; Wang, Nannan; Peng, Yan; Ma, Wen; Dai, Ronghua.

Affiliation

Bian Q; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Wang W; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Wang N; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Peng Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Ma W; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Dai R; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: ronghuadai@sina.com.

J Pharm Biomed Anal ; 128: 149-157, 2016 Sep 05.

Article in En | MEDLINE | ID: mdl-27262108

Subject(s)

Arachidonic Acid/metabolism; Prostatic Hyperplasia/metabolism; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid/metabolism; Animals; Biomarkers/metabolism; Chromatography, High Pressure Liquid/methods; Drugs, Chinese Herbal/metabolism; Hydroxyeicosatetraenoic Acids/metabolism; Lipoxygenase/metabolism; Male; Medicine, Chinese Traditional/methods; Metabolomics/methods; Plasma/metabolism; Prostaglandin-Endoperoxide Synthases/metabolism; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry/methods

Key words

Arachidonic acid; Benign prostatic hyperplasia; Biomarkers; Eicosanoids; UHPLCMS/MS; Zishen pill

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Prostatic Hyperplasia / Arachidonic Acid Type of study: Diagnostic_studies Language: En Journal: J Pharm Biomed Anal Year: 2016 Type: Article Affiliation country: China

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