OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens.

Aljayyoussi, Ghaith; Kay, Katherine; Ward, Stephen A; Biagini, Giancarlo A

Aljayyoussi, Ghaith; Kay, Katherine; Ward, Stephen A; Biagini, Giancarlo A.

Affiliation

Aljayyoussi G; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.
Kay K; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.
Ward SA; State University of New York at Buffalo, Buffalo, NY, 14214, USA.
Biagini GA; Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.

Malar J ; 15(1): 344, 2016 07 07.

Article in En | MEDLINE | ID: mdl-27388207

Subject(s)

Antimalarials/pharmacology; Antimalarials/pharmacokinetics; Drug Evaluation, Preclinical/methods; Internet; Malaria/drug therapy; Software; Antimalarials/isolation & purification; Humans; Models, Theoretical

Key words

ADMET; Artemisinin; DMPK; Drug discovery; Lead optimisation; Malaria; Medicinal chemistry; PK/PD modelling; Pharmacokinetics; Plasmodium; Pre-clinical

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Full text: 1 Database: MEDLINE Main subject: Software / Internet / Drug Evaluation, Preclinical / Malaria / Antimalarials Type of study: Prognostic_studies Language: En Journal: Malar J Year: 2016 Type: Article Affiliation country: United kingdom

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