The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis.

Zhang, Qian; Bertics, Sandra J; Luchini, N Daniel; White, Heather M

Zhang, Qian; Bertics, Sandra J; Luchini, N Daniel; White, Heather M.

Affiliation

Zhang Q; Department of Dairy Science, University of Wisconsin, Madison 53706.
Bertics SJ; Department of Dairy Science, University of Wisconsin, Madison 53706.
Luchini ND; Adisseo, Alpharetta, GA 30022.
White HM; Department of Dairy Science, University of Wisconsin, Madison 53706. Electronic address: heather.white@wisc.edu.

J Dairy Sci ; 99(10): 8451-8460, 2016 Oct.

Article in En | MEDLINE | ID: mdl-27474977

Subject(s)

Liver/drug effects; Methionine/analogs & derivatives; Methionine/pharmacology; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase/genetics; Adenosylhomocysteinase/genetics; Animals; Animals, Newborn; Betaine/metabolism; Betaine-Homocysteine S-Methyltransferase/genetics; Carnitine O-Palmitoyltransferase/genetics; Cattle; Down-Regulation; Gluconeogenesis/genetics; Glucose-6-Phosphatase/genetics; Hepatocytes/drug effects; Hepatocytes/metabolism; Homocysteine/metabolism; Liver/metabolism; Methionine Adenosyltransferase/genetics; Methylenetetrahydrofolate Reductase (NADPH2)/genetics; Phosphoenolpyruvate Carboxykinase (GTP)/genetics; S-Adenosylmethionine/metabolism; Up-Regulation

Key words

2-hydroxy-4-(methylthio) butanoic acid (HMB); gluconeogenesis; methionine cycle; methyl donor

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Full text: 1 Database: MEDLINE Main subject: Liver / Methionine Language: En Journal: J Dairy Sci Year: 2016 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Liver / Methionine Language: En Journal: J Dairy Sci Year: 2016 Type: Article