Intranasal oxytocin administration improves depression-like behaviors in adult rats that experienced neonatal maternal deprivation.

Ji, Haoyi; Su, Wenlong; Zhou, Ruchen; Feng, Jing; Lin, Yue; Zhang, Yumin; Wang, Xinmei; Chen, Xiaoyang; Li, Jing

Ji, Haoyi; Su, Wenlong; Zhou, Ruchen; Feng, Jing; Lin, Yue; Zhang, Yumin; Wang, Xinmei; Chen, Xiaoyang; Li, Jing.

Affiliation

Ji H; aShandong Provincial Key Laboratory of Mental Disorders, Department of Physiology bDepartment of Medical Ethics, Shandong University School of Medicine, Jinan cDepartment of Pathology, Central Hospital of Zibo, Zibo, Shandong, China.

Behav Pharmacol ; 27(8): 689-696, 2016 12.

Article in En | MEDLINE | ID: mdl-27644094

Subject(s)

Depression/drug therapy; Neurogenesis/drug effects; Oxytocin/administration & dosage; Stress, Psychological/drug therapy; Administration, Intranasal; Animals; Animals, Newborn; Depression/etiology; Hippocampus/drug effects; Hippocampus/metabolism; Hypothalamus/drug effects; Hypothalamus/metabolism; Male; Maternal Deprivation; Oxytocin/metabolism; Oxytocin/pharmacology; Rats; Rats, Sprague-Dawley; Social Behavior; Stress, Psychological/etiology

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Database: MEDLINE Main subject: Stress, Psychological / Oxytocin / Depression / Neurogenesis Type of study: Etiology_studies Language: En Journal: Behav Pharmacol Year: 2016 Type: Article Affiliation country: China

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