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Energy metabolism in fracture healing. Measurement of adenosine triphosphate in callus to monitor progress.
Leung, K S; Sher, A H; Lam, T S; Leung, P C.
Affiliation
  • Leung KS; Chinese University of Hong Kong.
J Bone Joint Surg Br ; 71(4): 657-60, 1989 Aug.
Article in En | MEDLINE | ID: mdl-2768316
We measured the adenosine triphosphate (ATP) content of callus at various intervals during healing in 78 fractured tibiae in 10- to 12-week-old rabbits. The results, compared with the level in normal tissues, showed a high rate of energy metabolism in the early phase of fracture healing, which persisted until the callus was corticalised and remodelling had started. The ATP content could provide a more sensitive index to monitor fracture healing in animal studies. Our findings lend support to the need for nutritional supplements for patients with multiple fractures.
Subject(s)
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Database: MEDLINE Main subject: Wound Healing / Bony Callus / Adenosine Triphosphate / Fractures, Bone Language: En Journal: J Bone Joint Surg Br Year: 1989 Type: Article
Search on Google
Database: MEDLINE Main subject: Wound Healing / Bony Callus / Adenosine Triphosphate / Fractures, Bone Language: En Journal: J Bone Joint Surg Br Year: 1989 Type: Article