Combination therapy with vancomycin-loaded calcium sulfate and vancomycin-loaded PMMA in the treatment of chronic osteomyelitis.

Luo, Shanchao; Jiang, Tongmeng; Yang, Yingnian; Yang, Xiaoping; Zhao, Jinmin

Luo, Shanchao; Jiang, Tongmeng; Yang, Yingnian; Yang, Xiaoping; Zhao, Jinmin.

Affiliation

Luo S; Department of Orthopaedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China.
Jiang T; Yulin Orthopedics Hospital of Chinese and Western Medicine, 537000, Yulin, Guangxi, China.
Yang Y; Department of Orthopaedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China.
Yang X; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Guangxi Medical University, 530021, Nanning, Guangxi, China.
Zhao J; Yulin Orthopedics Hospital of Chinese and Western Medicine, 537000, Yulin, Guangxi, China.

BMC Musculoskelet Disord ; 17(1): 502, 2016 12 22.

Article in En | MEDLINE | ID: mdl-28007027

Subject(s)

Anti-Bacterial Agents/therapeutic use; Calcium Sulfate/chemistry; Drug Carriers/chemistry; Drug Delivery Systems/instrumentation; Osteomyelitis/drug therapy; Polymethyl Methacrylate/chemistry; Postoperative Complications/drug therapy; Vancomycin/therapeutic use; Adolescent; Adult; Aged; Anti-Bacterial Agents/administration & dosage; Anti-Bacterial Agents/adverse effects; Bone and Bones/injuries; Calcium Sulfate/adverse effects; Case-Control Studies; Chronic Disease; Debridement; Drug Carriers/adverse effects; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Orthopedic Procedures/adverse effects; Osteomyelitis/blood; Osteomyelitis/etiology; Osteomyelitis/surgery; Polymethyl Methacrylate/adverse effects; Postoperative Complications/blood; Postoperative Complications/etiology; Reoperation; Retrospective Studies; Vancomycin/administration & dosage; Vancomycin/adverse effects; Young Adult

Key words

Antibiotic; Calcium Sulfate; Debridement; Level of Evidence Level III; Osteomyelitis; PMMA; Retrospective trial

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Osteomyelitis / Postoperative Complications / Calcium Sulfate / Drug Carriers / Vancomycin / Drug Delivery Systems / Polymethyl Methacrylate / Anti-Bacterial Agents Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: BMC Musculoskelet Disord Year: 2016 Type: Article Affiliation country: China

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