Moderate doses of commercial preparations of Ginkgo biloba do not alter markers of liver function but moderate alcohol intake does: A new approach to identify and quantify biomarkers of 'adverse effects' of dietary supplements.

Lieberman, Harris R; Kellogg, Mark D; Fulgoni, Victor L; Agarwal, Sanjiv

Lieberman, Harris R; Kellogg, Mark D; Fulgoni, Victor L; Agarwal, Sanjiv.

Affiliation

Lieberman HR; Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, USA. Electronic address: harris.r.lieberman.civ@mail.mil.
Kellogg MD; Department of Laboratory Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA. Electronic address: mark.kellogg@childrens.harvard.edu.
Fulgoni VL; Oak Ridge Institute for Science and Education, Belcamp, MD 21017, USA; Henry M. Jackson Foundation, Bethesda, MD 20817, USA. Electronic address: vic3rd@aol.com.
Agarwal S; Oak Ridge Institute for Science and Education, Belcamp, MD 21017, USA. Electronic address: agarwal47@yahoo.com.

Regul Toxicol Pharmacol ; 84: 45-53, 2017 Mar.

Article in En | MEDLINE | ID: mdl-28025058

Subject(s)

Alcohol Drinking/adverse effects; Chemical and Drug Induced Liver Injury/epidemiology; Dietary Supplements/adverse effects; Ginkgo biloba/adverse effects; Liver Diseases, Alcoholic/epidemiology; Liver/drug effects; Plant Extracts/adverse effects; Adult; Chemical and Drug Induced Liver Injury/blood; Chemical and Drug Induced Liver Injury/diagnosis; Clinical Enzyme Tests; Consumer Product Safety; Cross-Sectional Studies; Female; Ginkgo biloba/chemistry; Humans; Liver/enzymology; Liver Diseases, Alcoholic/blood; Liver Diseases, Alcoholic/diagnosis; Liver Function Tests; Male; Middle Aged; Nutrition Surveys; Phytotherapy; Plant Extracts/isolation & purification; Plant Leaves; Plants, Medicinal; Predictive Value of Tests; Risk Assessment; Risk Factors; United States/epidemiology

Key words

Alanine aminotransferase; Aspartate aminotransferase; Bilirubin; Gamma glutamyl transferase; Lactate dehydrogenase; NHANES

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Alcohol Drinking / Plant Extracts / Dietary Supplements / Ginkgo biloba / Chemical and Drug Induced Liver Injury / Liver / Liver Diseases, Alcoholic Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Country/Region as subject: America do norte Language: En Journal: Regul Toxicol Pharmacol Year: 2017 Type: Article

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