Neuroprotective effect and mechanism of daucosterol palmitate in ameliorating learning and memory impairment in a rat model of Alzheimer's disease.

Ji, Zhi-Hong; Xu, Zhong-Qi; Zhao, Hong; Yu, Xin-Yu

Ji, Zhi-Hong; Xu, Zhong-Qi; Zhao, Hong; Yu, Xin-Yu.

Affiliation

Ji ZH; Laboratory of Neuroscience, College of Medicine, Dalian University, Dalian 116622, People's Republic of China.
Xu ZQ; Laboratory of Neuroscience, College of Medicine, Dalian University, Dalian 116622, People's Republic of China.
Zhao H; Department of Traditional Chinese Medicine, College of Medicine, Dalian University, Dalian 116622, People's Republic of China.
Yu XY; Laboratory of Neuroscience, College of Medicine, Dalian University, Dalian 116622, People's Republic of China. Electronic address: xybio@sina.com.

Steroids ; 119: 31-35, 2017 03.

Article in En | MEDLINE | ID: mdl-28119081

Subject(s)

Cognition Disorders/drug therapy; Learning/drug effects; Memory/drug effects; Sitosterols/therapeutic use; Alzheimer Disease/drug therapy; Alzheimer Disease/metabolism; Alzheimer Disease/physiopathology; Amyloid beta-Peptides/toxicity; Animals; Cognition Disorders/metabolism; Cognition Disorders/physiopathology; Hippocampus/cytology; Male; Neurons/drug effects; Neurons/metabolism; Rats; Rats, Wistar; Reactive Oxygen Species/metabolism; Synaptophysin/metabolism

Key words

Alzheimer's disease; Daucosterol palmitate; Hippocampal neurons; Learning and memory; Reactive oxygen species; Synaptophysin

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Sitosterols / Cognition Disorders / Learning / Memory Language: En Journal: Steroids Year: 2017 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Sitosterols / Cognition Disorders / Learning / Memory Language: En Journal: Steroids Year: 2017 Type: Article