Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates.

Lundsgaard, Anne-Marie; Fritzen, Andreas M; Sjøberg, Kim A; Myrmel, Lene S; Madsen, Lise; Wojtaszewski, Jørgen F P; Richter, Erik A; Kiens, Bente

Lundsgaard, Anne-Marie; Fritzen, Andreas M; Sjøberg, Kim A; Myrmel, Lene S; Madsen, Lise; Wojtaszewski, Jørgen F P; Richter, Erik A; Kiens, Bente.

Affiliation

Lundsgaard AM; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Fritzen AM; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Sjøberg KA; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Myrmel LS; National Institute of Nutrition and Seafood Research, Bergen, Norway.
Madsen L; National Institute of Nutrition and Seafood Research, Bergen, Norway; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Wojtaszewski JFP; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Richter EA; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Kiens B; Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. Electronic address: bkiens@nexs.ku.dk.

Mol Metab ; 6(1): 22-29, 2017 01.

Article in En | MEDLINE | ID: mdl-28123934

Subject(s)

Dietary Carbohydrates/administration & dosage; Fibroblast Growth Factors/metabolism; Adult; Dietary Fats/administration & dosage; Dietary Fats/metabolism; Dietary Proteins/administration & dosage; Dietary Proteins/metabolism; Energy Intake; Energy Metabolism/physiology; Fibroblast Growth Factors/blood; Glucose/metabolism; Humans; Insulin/blood; Lipogenesis/physiology; Liver/metabolism; Male

Key words

AMPK, AMP-activated kinase; ATGL, adipose triglyceride lipase; BCA, bicinchoninic acid; BM, body mass; BMI, body mass index; CHO, carbohydrate-rich diet; CON, control diet; Carbohydrates; ChREBP, carbohydrate-responsive element binding protein; Diet; FA, fatty acid; FAT, fat-rich diet; FGF21; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter 4; HSL, hormone sensitive lipase; LM, leg mass; Lipolysis; Liver; PKA, protein kinase A; Ra, rate of appearance; TG, triacylglycerol; VLDL, very low density lipoprotein; VO2peak, maximal oxygen consumption

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Full text: 1 Database: MEDLINE Main subject: Dietary Carbohydrates / Fibroblast Growth Factors Language: En Journal: Mol Metab Year: 2017 Type: Article Affiliation country: Denmark

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