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The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata.
Huang, Yiyou; Liu, Xin; Wu, Deyan; Tang, Guihua; Lai, Zengwei; Zheng, Xuehua; Yin, Sheng; Luo, Hai-Bin.
Affiliation
  • Huang Y; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Liu X; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Wu D; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Tang G; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Lai Z; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Zheng X; School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China. Electronic address: zhengxh23@gzhmu.edu.cn.
  • Yin S; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China. Electronic address: yinsh2@mail.sysu.edu.cn.
  • Luo HB; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China; Collaborative Innovation Center of High Performance Computing, National University of Defense Technology, Changsha 410073, China. Electronic address: luohb77@mail.sysu.edu.cn.
Biochem Pharmacol ; 130: 51-59, 2017 04 15.
Article in En | MEDLINE | ID: mdl-28159622
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Selaginellaceae / Phosphodiesterase 4 Inhibitors Language: En Journal: Biochem Pharmacol Year: 2017 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Selaginellaceae / Phosphodiesterase 4 Inhibitors Language: En Journal: Biochem Pharmacol Year: 2017 Type: Article Affiliation country: China