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Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.
Mardinoglu, Adil; Bjornson, Elias; Zhang, Cheng; Klevstig, Martina; Söderlund, Sanni; Ståhlman, Marcus; Adiels, Martin; Hakkarainen, Antti; Lundbom, Nina; Kilicarslan, Murat; Hallström, Björn M; Lundbom, Jesper; Vergès, Bruno; Barrett, Peter Hugh R; Watts, Gerald F; Serlie, Mireille J; Nielsen, Jens; Uhlén, Mathias; Smith, Ulf; Marschall, Hanns-Ulrich; Taskinen, Marja-Riitta; Boren, Jan.
Affiliation
  • Mardinoglu A; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden adilm@scilifelab.se jan.boren@wlab.gu.se.
  • Bjornson E; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
  • Zhang C; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
  • Klevstig M; Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Söderlund S; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Ståhlman M; Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Adiels M; Research programs Unit, Diabetes and Obesity, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
  • Hakkarainen A; Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Lundbom N; Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Kilicarslan M; Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.
  • Hallström BM; Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.
  • Lundbom J; Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Vergès B; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Barrett PH; Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.
  • Watts GF; Department of Endocrinology-Diabetology, University Hospital and INSERM CRI 866, Dijon, France.
  • Serlie MJ; Faculty of Engineering, Computing and Mathematics, University of Western Australia, Perth, WA, Australia.
  • Nielsen J; Metabolic Research Centre, Cardiovascular Medicine, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.
  • Uhlén M; Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Smith U; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Marschall HU; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
  • Taskinen MR; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.
  • Boren J; Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.
Mol Syst Biol ; 13(3): 916, 2017 03 02.
Article in En | MEDLINE | ID: mdl-28254760
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Full text: 1 Database: MEDLINE Main subject: Serine / Metabolomics / Non-alcoholic Fatty Liver Disease / Glutathione / Lipoproteins / NAD Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Mol Syst Biol Year: 2017 Type: Article
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Serine / Metabolomics / Non-alcoholic Fatty Liver Disease / Glutathione / Lipoproteins / NAD Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Mol Syst Biol Year: 2017 Type: Article