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Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog.
Tanner, Mark R; Tajhya, Rajeev B; Huq, Redwan; Gehrmann, Elizabeth J; Rodarte, Kathia E; Atik, Mustafa A; Norton, Raymond S; Pennington, Michael W; Beeton, Christine.
Affiliation
  • Tanner MR; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA; Interdepartmental Graduate Program in Translational Biology & Molecular Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Tajhya RB; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA; Graduate Program in Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Huq R; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA; Graduate Program in Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Gehrmann EJ; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Rodarte KE; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Atik MA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Norton RS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Pennington MW; Peptides International, 11621 Electron Drive, Louisville, KY 40299, USA.
  • Beeton C; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX 77030, USA; Biology of Inflammation Center and Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: beeton@bcm.edu.
Clin Immunol ; 180: 45-57, 2017 07.
Article in En | MEDLINE | ID: mdl-28389388
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Full text: 1 Database: MEDLINE Main subject: Peptides / Polyethylene Glycols / Scorpion Venoms / Potassium Channel Blockers / Kv1.3 Potassium Channel Type of study: Prognostic_studies Language: En Journal: Clin Immunol Year: 2017 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Peptides / Polyethylene Glycols / Scorpion Venoms / Potassium Channel Blockers / Kv1.3 Potassium Channel Type of study: Prognostic_studies Language: En Journal: Clin Immunol Year: 2017 Type: Article Affiliation country: United States