Mesenteric lymph node CD11b- CD103+ PD-L1High dendritic cells highly induce regulatory T cells.

Shiokawa, Aya; Kotaki, Ryutaro; Takano, Tomohiro; Nakajima-Adachi, Haruyo; Hachimura, Satoshi

Mesenteric lymph node CD11b^- CD103⁺ PD-L1^High dendritic cells highly induce regulatory T cells.

Shiokawa, Aya; Kotaki, Ryutaro; Takano, Tomohiro; Nakajima-Adachi, Haruyo; Hachimura, Satoshi.

Affiliation

Shiokawa A; Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Kotaki R; Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Takano T; Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Nakajima-Adachi H; Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Hachimura S; Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Immunology ; 152(1): 52-64, 2017 09.

Article in En | MEDLINE | ID: mdl-28423181

Subject(s)

Antigens, CD/immunology; B7-H1 Antigen/immunology; CD11b Antigen/immunology; Cell Communication; Dendritic Cells/immunology; Integrin alpha Chains/immunology; Intestines/immunology; Lymph Nodes/immunology; T-Lymphocytes, Regulatory/immunology; Administration, Oral; Aldehyde Dehydrogenase/immunology; Aldehyde Dehydrogenase/metabolism; Aldehyde Dehydrogenase 1 Family; Animals; Antigens, CD/metabolism; B7-H1 Antigen/metabolism; CD11b Antigen/metabolism; Cell Communication/drug effects; Cell Movement; Cells, Cultured; Coculture Techniques; Dendritic Cells/drug effects; Dendritic Cells/metabolism; Forkhead Transcription Factors/immunology; Forkhead Transcription Factors/metabolism; Immunity, Mucosal; Integrin alpha Chains/metabolism; Integrin beta Chains/immunology; Integrin beta Chains/metabolism; Intestinal Mucosa/metabolism; Intestines/cytology; Intestines/drug effects; Lymph Nodes/cytology; Lymph Nodes/drug effects; Lymph Nodes/metabolism; Mesentery; Mice, Inbred BALB C; Ovalbumin/administration & dosage; Ovalbumin/immunology; Phenotype; Retinal Dehydrogenase; Signal Transduction; T-Lymphocytes, Regulatory/drug effects; T-Lymphocytes, Regulatory/metabolism; Transforming Growth Factor beta/immunology; Transforming Growth Factor beta/metabolism; Tretinoin/pharmacology

Key words

dendritic cells; intestinal immunity; mesenteric lymph nodes; oral tolerance; regulatory T cells

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Antigens, CD / Cell Communication / T-Lymphocytes, Regulatory / Integrin alpha Chains / CD11b Antigen / B7-H1 Antigen / Intestines / Lymph Nodes Type of study: Prognostic_studies Language: En Journal: Immunology Year: 2017 Type: Article Affiliation country: Japan

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