Metabolic Effect of 1-Deoxynojirimycin from Mulberry Leaves on db/db Diabetic Mice Using Liquid Chromatography-Mass Spectrometry Based Metabolomics.

Hu, Xue-Qin; Thakur, Kiran; Chen, Gui-Hai; Hu, Fei; Zhang, Jian-Guo; Zhang, Hong-Bin; Wei, Zhao-Jun

Hu, Xue-Qin; Thakur, Kiran; Chen, Gui-Hai; Hu, Fei; Zhang, Jian-Guo; Zhang, Hong-Bin; Wei, Zhao-Jun.

Affiliation

Chen GH; Department of Neurology, The Affiliated Chaohu Hospital of Anhui Medical University, Chaohu , Hefei 238000, People's Republic of China.

J Agric Food Chem ; 65(23): 4658-4667, 2017 Jun 14.

Article in En | MEDLINE | ID: mdl-28541040

Subject(s)

1-Deoxynojirimycin/metabolism; Diabetes Mellitus, Type 2/drug therapy; Hypoglycemic Agents/metabolism; Morus/chemistry; Plant Extracts/metabolism; Plant Leaves/chemistry; 1-Deoxynojirimycin/administration & dosage; 1-Deoxynojirimycin/analysis; Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2/metabolism; Humans; Hypoglycemic Agents/administration & dosage; Hypoglycemic Agents/analysis; Insulin; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Inbred C57BL; Morus/metabolism; Plant Extracts/administration & dosage; Plant Extracts/chemistry; Plant Leaves/metabolism

Key words

1-deoxynojirimycin; LC−MS; metabolomics; mulberry; type 2 diabetes; urinary metabolites

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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / 1-Deoxynojirimycin / Plant Leaves / Morus / Diabetes Mellitus, Type 2 / Hypoglycemic Agents Language: En Journal: J Agric Food Chem Year: 2017 Type: Article

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