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Frequency-dependent drug screening using optogenetic stimulation of human iPSC-derived cardiomyocytes.
Lapp, Hendrik; Bruegmann, Tobias; Malan, Daniela; Friedrichs, Stephanie; Kilgus, Carsten; Heidsieck, Alexandra; Sasse, Philipp.
Affiliation
  • Lapp H; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
  • Bruegmann T; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
  • Malan D; Research Training Group 1873, University of Bonn, 53127, Bonn, Germany.
  • Friedrichs S; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
  • Kilgus C; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
  • Heidsieck A; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
  • Sasse P; Zentralinstitut für Medizintechnik, Technische Universität München, München, Germany.
Sci Rep ; 7(1): 9629, 2017 08 29.
Article in En | MEDLINE | ID: mdl-28851973
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Full text: 1 Database: MEDLINE Main subject: Myocytes, Cardiac / Drug Evaluation, Preclinical / Induced Pluripotent Stem Cells / Optogenetics Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Sci Rep Year: 2017 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Myocytes, Cardiac / Drug Evaluation, Preclinical / Induced Pluripotent Stem Cells / Optogenetics Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Sci Rep Year: 2017 Type: Article Affiliation country: Germany