Cholesterol regulates polymodal sensory transduction in Müller glia.

Lakk, Monika; Yarishkin, Oleg; Baumann, Jackson M; Iuso, Anthony; Krizaj, David

Lakk, Monika; Yarishkin, Oleg; Baumann, Jackson M; Iuso, Anthony; Krizaj, David.

Affiliation

Lakk M; Departments of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah.
Yarishkin O; Departments of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah.
Baumann JM; Bioengineering, University of Utah, Salt Lake City, Utah.
Iuso A; Departments of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah.
Krizaj D; Departments of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah.

Glia ; 65(12): 2038-2050, 2017 12.

Article in En | MEDLINE | ID: mdl-28856727

Subject(s)

Cholesterol/metabolism; Ependymoglial Cells/metabolism; Signal Transduction/physiology; Animals; Calcium/metabolism; Caveolin 1/genetics; Caveolin 1/metabolism; Cells, Cultured; Cholesterol/pharmacology; Ependymoglial Cells/drug effects; Female; Leucine/analogs & derivatives; Leucine/pharmacology; Male; Membrane Microdomains; Membrane Potentials/drug effects; Membrane Potentials/genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Retina/cytology; Signal Transduction/genetics; Sulfonamides/pharmacology; TRPV Cation Channels/agonists; TRPV Cation Channels/genetics; TRPV Cation Channels/metabolism; Temperature

Key words

TRPV4; cyclodextrin; hypercholesterolemia; lipid raft; swelling

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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Cholesterol / Ependymoglial Cells Language: En Journal: Glia Year: 2017 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Cholesterol / Ependymoglial Cells Language: En Journal: Glia Year: 2017 Type: Article