Modulatory effect of caffeic acid on cholinesterases inhibitory properties of donepezil.

Agunloye, Odunayo Michael; Oboh, Ganiyu

Agunloye, Odunayo Michael; Oboh, Ganiyu.

Affiliation

Agunloye OM; Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, P.M.B 704, Akure 340001, Nigeria.
Oboh G; Department of Biochemistry, Federal University of Technology Akure, Akure, Nigeria.

J Complement Integr Med ; 15(1)2017 Sep 22.

Article in En | MEDLINE | ID: mdl-28941354

Subject(s)

Acetylcholinesterase/chemistry; Alzheimer Disease/drug therapy; Butyrylcholinesterase/chemistry; Caffeic Acids/chemistry; Cholinesterase Inhibitors/chemistry; Indans/chemistry; Piperidines/chemistry; Acetylcholinesterase/metabolism; Alzheimer Disease/enzymology; Animals; Butyrylcholinesterase/metabolism; Caffeic Acids/administration & dosage; Cholinesterase Inhibitors/administration & dosage; Donepezil; Drug Synergism; Drug Therapy, Combination; Humans; Indans/administration & dosage; Male; Nootropic Agents/administration & dosage; Nootropic Agents/chemistry; Piperidines/administration & dosage; Rats; Rats, Wistar

Key words

Alzheimer's disease; acetylcholinesterase; butyrylcholinesterase; caffeic acid; donepezil

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Full text: 1 Database: MEDLINE Main subject: Piperidines / Acetylcholinesterase / Butyrylcholinesterase / Caffeic Acids / Cholinesterase Inhibitors / Alzheimer Disease / Indans Language: En Journal: J Complement Integr Med Year: 2017 Type: Article Affiliation country: Nigeria

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