Tissue specific effects of feeds supplemented with grape pomace or olive oil mill wastewater on detoxification enzymes in sheep.

Kerasioti, Efthalia; Terzopoulou, Zoi; Komini, Ourania; Kafantaris, Ioannis; Makri, Sotiria; Stagos, Dimitrios; Gerasopoulos, Konstantinos; Anisimov, Nikita Y; Tsatsakis, Aristides M; Kouretas, Demetrios.

Affiliation

Kerasioti E; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Terzopoulou Z; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Komini O; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Kafantaris I; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Makri S; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Stagos D; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Gerasopoulos K; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.
Anisimov NY; School of Engineering, Federal Far East University, Russia.
Tsatsakis AM; Department of Forensic Sciences and Toxicology, Medical School, University of Crete, Heraklion 71003, Greece.
Kouretas D; Department of Biochemistry-Biotechnology, University of Thessaly, Larissa 41500, Greece.

Toxicol Rep ; 4: 364-372, 2017.

Article in En | MEDLINE | ID: mdl-28959661

Key words

AREs, antioxidant response elements; CDNB, 1 chloro-2,4-dinitrobenzene; DETAPAC, diethylenetriaminepentaacetic acid; DTT, dithiothreitol; GAPDH, glyceraldehyde 3-phosphatedehydrogenase; GP, grape pomace; GS, glutathione synthase; GSH, glutathione; GST, glutathione-s-transferase; Glutathione-s-transferase (GST); Grape pomace (GP); HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; KCl, potassium chloride; KOH, potassium hydroxide; Keap1, kelch-like ECH-associated protein 1; MgCl2, magnesium chloride; NBT, nitroblue tetrazolium; NaCl, sodium chloride; Nrf2, nuclear factor-like 2; OMW, olive oil mill wastewater; Olive oil mill wastewater (OMW); PVDF, polyvinylidene difluoride membranes; ROS, reactive oxygen species; SDS, sodium dodecyl sulfate; SOD, superoxide dismutase; Superoxide dismutase (SOD); XO, xanthine oxidase; Î³-GCS, Î³-synthase glutamyl cysteine; Î³-synthase glutamyl custeine (Î³-GCS)