Acupuncture inhibits TXNIP-associated oxidative stress and inflammation to attenuate cognitive impairment in vascular dementia rats.

Du, Si-Qi; Wang, Xue-Rui; Zhu, Wen; Ye, Yang; Yang, Jing-Wen; Ma, Si-Ming; Ji, Cai-Shuo; Liu, Cun-Zhi

Du, Si-Qi; Wang, Xue-Rui; Zhu, Wen; Ye, Yang; Yang, Jing-Wen; Ma, Si-Ming; Ji, Cai-Shuo; Liu, Cun-Zhi.

Affiliation

Du SQ; Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, Beijing, China.
Wang XR; Beijing Key Laboratory of Acupuncture Neuromodulation, Beijing, China.
Zhu W; Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, Beijing, China.
Ye Y; Beijing Key Laboratory of Acupuncture Neuromodulation, Beijing, China.
Yang JW; Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, Beijing, China.
Ma SM; Beijing Key Laboratory of Acupuncture Neuromodulation, Beijing, China.
Ji CS; Beijing University of Chinese Medicine, Beijing, China.
Liu CZ; Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, Beijing, China.

CNS Neurosci Ther ; 24(1): 39-46, 2018 Jan.

Article in En | MEDLINE | ID: mdl-29110407

Subject(s)

Acupuncture Therapy/methods; Carrier Proteins/metabolism; Cognition Disorders/etiology; Cognition Disorders/therapy; Dementia, Vascular/complications; Oxidative Stress/physiology; Animals; Carrier Proteins/genetics; Caspase 3/metabolism; Cell Cycle Proteins; Dementia, Vascular/pathology; Disease Models, Animal; Gene Expression Regulation/physiology; Hippocampus/metabolism; Hippocampus/pathology; Inflammasomes/metabolism; Interleukin-1beta/genetics; Interleukin-1beta/metabolism; Male; Maze Learning/physiology; NLR Family, Pyrin Domain-Containing 3 Protein/genetics; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism; Phosphopyruvate Hydratase/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Rats; Rats, Wistar; Reactive Oxygen Species/metabolism; Superoxide Dismutase/metabolism

Key words

cognitive impairment; inflammation; oxidative stress; thioredoxin-interacting protein; vascular dementia

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Therapeutic Methods and Therapies TCIM: Terapias_manuales Main subject: Dementia, Vascular / Carrier Proteins / Acupuncture Therapy / Cognition Disorders / Oxidative Stress Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: CNS Neurosci Ther Year: 2018 Type: Article Affiliation country: China

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