Soybean amplifies the hypohomocysteinemic effect of betaine and improves its hypercholesterolemic effect.

Shimada, Ryoko; Ebihara, Kiyoshi

Shimada, Ryoko; Ebihara, Kiyoshi.

Affiliation

Shimada R; a Faculty of Health Sciences , Osaka Aoyama University , Osaka , Japan.
Ebihara K; a Faculty of Health Sciences , Osaka Aoyama University , Osaka , Japan.

Biosci Biotechnol Biochem ; 82(4): 669-676, 2018 Apr.

Article in En | MEDLINE | ID: mdl-29207911

Subject(s)

Glycine max; Homocysteine/blood; Hypercholesterolemia/prevention & control; Animal Feed; Animals; Betaine/administration & dosage; Bile Acids and Salts/metabolism; Body Weight; Caseins/administration & dosage; Cholesterol/blood; Feces; Gene Expression; Hypercholesterolemia/diet therapy; Lecithins/administration & dosage; Liver/metabolism; Male; Organ Size; Rats, Wistar; Soybean Proteins/administration & dosage; Triglycerides/blood

Key words

BHMT, betaine-homocysteine-S-methyltransferase; Betaine; CBS, cystathionine ß-synthesis; CYP7A1, cholesterol 7α-hydroxylase; HMG-CoA reductase, hydroxymethylglutaryl-CoA reductase; Hcy, homocysteine; MS, methionine synthesis; MTP, microsomal triglyceride transfer protein; SAH, S-adenosyl-L-homocysteine; SAM, S-adenosylmethionine, SPI, soy protein isolate; SB, soybean; SF, soy fiber; SL, soy lecithin; TG, triglyceride; plasma cholesterol; plasma homocysteine; soy protein isolate; soybean

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Full text: 1 Database: MEDLINE Main subject: Glycine max / Homocysteine / Hypercholesterolemia Language: En Journal: Biosci Biotechnol Biochem Year: 2018 Type: Article Affiliation country: Japan

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