Palmitate-induced insulin resistance is attenuated by Pioglitazone and EGCG through reducing the gluconeogenic key enzymes expression in HepG2 cells.

Yadollah, S; Kazemipour, N; Bakhtiyari, S; Nazifi, S

Yadollah, S; Kazemipour, N; Bakhtiyari, S; Nazifi, S.

Affiliation

Yadollah S; Department of Basic Science, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Kazemipour N; Department of Basic Science, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Bakhtiyari S; Department of Clinical Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Nazifi S; Department of Clinical Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

J Med Life ; 10(4): 244-249, 2017.

Article in En | MEDLINE | ID: mdl-29362600

Subject(s)

Catechin/analogs & derivatives; Gene Expression Regulation, Enzymologic/drug effects; Gluconeogenesis/drug effects; Glucosephosphate Dehydrogenase/genetics; Insulin Resistance; Palmitates/adverse effects; Phosphoenolpyruvate Carboxykinase (ATP)/genetics; Thiazolidinediones/pharmacology; Catechin/pharmacology; Glucose/metabolism; Glucosephosphate Dehydrogenase/metabolism; Hep G2 Cells; Humans; Phosphoenolpyruvate Carboxykinase (ATP)/metabolism; Pioglitazone; RNA, Messenger/genetics; RNA, Messenger/metabolism

Key words

epigallocatechin gallate (EGCG); gluconeogenesis; glucose 6-phosphatase; phosphoenolpyruvate carboxykinase; pioglitazone

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Full text: 1 Database: MEDLINE Main subject: Palmitates / Insulin Resistance / Catechin / Gene Expression Regulation, Enzymologic / Phosphoenolpyruvate Carboxykinase (ATP) / Thiazolidinediones / Gluconeogenesis / Glucosephosphate Dehydrogenase Language: En Journal: J Med Life Year: 2017 Type: Article Affiliation country: Iran

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