Valine Supplementation in a Reduced Protein Diet Regulates Growth Performance Partially through Modulation of Plasma Amino Acids Profile, Metabolic Responses, Endocrine, and Neural Factors in Piglets.
J Agric Food Chem
; 66(12): 3161-3168, 2018 Mar 28.
Article
in En
| MEDLINE
| ID: mdl-29526104
ABSTRACT
The objective of this study was to investigate whether valine (Val) supplementation in a reduced protein (RP) diet regulates growth performance associated with the changes in plasma amino acids (AAs) profile, metabolism, endocrine, and neural system in piglets. Piglets or piglets with a catheter in the precaval vein were randomly assigned to two treatments, including two RP diets with standardized ileal digestible (SID) ValLysine (Lys) ratio of 0.45 and 0.65, respectively. The results indicated that piglets in the higher ValLys ratio treatment had higher average daily feed intake (ADFI) ( P < 0.001), average daily gain (ADG) ( P = 0.001), feed conversion ratio (FCR) ( P = 0.004), lower plasma urea nitrogen ( P = 0.032), expression of gastric cholecystokinin (CCK), and hypothalamic pro-opiomelanocortin (POMC). Plasma AAs profiles including postprandial plasma essential AAs (EAAs) profile and in serum, muscle, and liver involved in metabolism of AAs and fatty acids were significantly different between two treatments. In conclusion, Val influenced growth performance associated with metabolism of AAs and fatty acids and both endocrine and neural system in piglets.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Swine
/
Valine
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Diet, Protein-Restricted
/
Endocrine System
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Amino Acids
/
Animal Feed
/
Nervous System
Language:
En
Journal:
J Agric Food Chem
Year:
2018
Type:
Article
Affiliation country:
China