Microwave hyperthermia promotes caspase­3-dependent apoptosis and induces G2/M checkpoint arrest via the ATM pathway in non­small cell lung cancer cells.

Zhao, Yan-Yan; Wu, Qiong; Wu, Zhi-Bing; Zhang, Jing-Jing; Zhu, Lu-Cheng; Yang, Yang; Ma, Sheng-Lin; Zhang, Shi-Rong

Microwave hyperthermia promotes caspase3-dependent apoptosis and induces G2/M checkpoint arrest via the ATM pathway in nonsmall cell lung cancer cells.

Zhao, Yan-Yan; Wu, Qiong; Wu, Zhi-Bing; Zhang, Jing-Jing; Zhu, Lu-Cheng; Yang, Yang; Ma, Sheng-Lin; Zhang, Shi-Rong.

Affiliation

Zhao YY; Center for Translational Medicine, Affiliated Hangzhou First People's Hospital of Nanjing Medical University, Hangzhou, Zhejiang 310006, P.R. China.
Wu Q; Center for Translational Medicine, Affiliated Hangzhou First People's Hospital of Nanjing Medical University, Hangzhou, Zhejiang 310006, P.R. China.
Wu ZB; Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, Zhejiang 310006, P.R. China.
Zhang JJ; Center for Translational Medicine, Affiliated Hangzhou First People's Hospital of Nanjing Medical University, Hangzhou, Zhejiang 310006, P.R. China.
Zhu LC; Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, Zhejiang 310006, P.R. China.
Yang Y; Department of Radiation Oncology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P.R. China.
Ma SL; Center for Translational Medicine, Affiliated Hangzhou First People's Hospital of Nanjing Medical University, Hangzhou, Zhejiang 310006, P.R. China.
Zhang SR; Center for Translational Medicine, Affiliated Hangzhou First People's Hospital of Nanjing Medical University, Hangzhou, Zhejiang 310006, P.R. China.

Int J Oncol ; 53(2): 539-550, 2018 Aug.

Article in En | MEDLINE | ID: mdl-29901106

Subject(s)

Carcinoma, Non-Small-Cell Lung/metabolism; Caspase 3/metabolism; Hyperthermia, Induced/methods; Lung Neoplasms/metabolism; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Non-Small-Cell Lung/therapy; Cell Line, Tumor; Cell Proliferation; Cell Survival; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/therapy; Microwaves; Phosphorylation; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects

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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Caspase 3 / Hyperthermia, Induced / Lung Neoplasms Language: En Journal: Int J Oncol Year: 2018 Type: Article

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