Effect of Zishenpingchan granule prepared from Chinese medicinal substances on the c-Jun N-terminal protein kinase pathway in mice with Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Ye, Qing; Yuan, Xiaolei; Zhou, Jie; Yuan, Canxing; Yang, Xuming

Ye, Qing; Yuan, Xiaolei; Zhou, Jie; Yuan, Canxing; Yang, Xuming.

J Tradit Chin Med ; 37(2): 244-51, 2017 04.

Article in En | MEDLINE | ID: mdl-29960635

Subject(s)

Drugs, Chinese Herbal/administration & dosage; JNK Mitogen-Activated Protein Kinases/metabolism; Neuroprotective Agents/administration & dosage; Parkinson Disease/drug therapy; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects; Animals; Apoptosis/drug effects; Cyclooxygenase 2/genetics; Cyclooxygenase 2/metabolism; Disease Models, Animal; Dopamine/metabolism; Humans; JNK Mitogen-Activated Protein Kinases/genetics; Male; Mice; Mice, Inbred C57BL; Parkinson Disease/enzymology; Parkinson Disease/genetics; Parkinson Disease/metabolism; Signal Transduction/drug effects; Substantia Nigra/enzymology; Substantia Nigra/metabolism; Tyrosine 3-Monooxygenase/genetics; Tyrosine 3-Monooxygenase/metabolism

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Parkinson Disease / Drugs, Chinese Herbal / Neuroprotective Agents / JNK Mitogen-Activated Protein Kinases Type of study: Prognostic_studies Language: En Journal: J Tradit Chin Med Year: 2017 Type: Article

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