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Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain.
De Gregorio, Danilo; McLaughlin, Ryan J; Posa, Luca; Ochoa-Sanchez, Rafael; Enns, Justine; Lopez-Canul, Martha; Aboud, Matthew; Maione, Sabatino; Comai, Stefano; Gobbi, Gabriella.
Affiliation
  • De Gregorio D; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • McLaughlin RJ; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA, United States.
  • Posa L; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Ochoa-Sanchez R; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada.
  • Enns J; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Lopez-Canul M; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Aboud M; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Maione S; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Comai S; Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Università degli Studi della Campania "Luigi Vanvitelli," Naples, Italy.
  • Gobbi G; Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada.
Pain ; 160(1): 136-150, 2019 Jan.
Article in En | MEDLINE | ID: mdl-30157131
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Anxiety / Cannabidiol / Serotonin / Hyperalgesia / Neuralgia Language: En Journal: Pain Year: 2019 Type: Article Affiliation country: Canada
Fulltext
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Anxiety / Cannabidiol / Serotonin / Hyperalgesia / Neuralgia Language: En Journal: Pain Year: 2019 Type: Article Affiliation country: Canada