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A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Mosley, Jonathan D; Feng, QiPing; Wells, Quinn S; Van Driest, Sara L; Shaffer, Christian M; Edwards, Todd L; Bastarache, Lisa; Wei, Wei-Qi; Davis, Lea K; McCarty, Catherine A; Thompson, Will; Chute, Christopher G; Jarvik, Gail P; Gordon, Adam S; Palmer, Melody R; Crosslin, David R; Larson, Eric B; Carrell, David S; Kullo, Iftikhar J; Pacheco, Jennifer A; Peissig, Peggy L; Brilliant, Murray H; Linneman, James G; Namjou, Bahram; Williams, Marc S; Ritchie, Marylyn D; Borthwick, Kenneth M; Verma, Shefali S; Karnes, Jason H; Weiss, Scott T; Wang, Thomas J; Stein, C Michael; Denny, Josh C; Roden, Dan M.
Affiliation
  • Mosley JD; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. jonathan.d.mosley@vanderbilt.edu.
  • Feng Q; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. jonathan.d.mosley@vanderbilt.edu.
  • Wells QS; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Van Driest SL; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Shaffer CM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Edwards TL; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Bastarache L; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Wei WQ; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Davis LK; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • McCarty CA; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Thompson W; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Chute CG; Essentia Institute of Rural Health, Duluth, MN, 55805, USA.
  • Jarvik GP; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
  • Gordon AS; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD, 21205, USA.
  • Palmer MR; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.
  • Crosslin DR; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.
  • Larson EB; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.
  • Carrell DS; Departments of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98195, USA.
  • Kullo IJ; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, 98195, USA.
  • Pacheco JA; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA.
  • Peissig PL; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA.
  • Brilliant MH; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 55905, USA.
  • Linneman JG; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
  • Namjou B; Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA.
  • Williams MS; Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA.
  • Ritchie MD; Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA.
  • Borthwick KM; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
  • Verma SS; Genomic Medicine Institute, Geisinger Health System, Danville, PA, 17822, USA.
  • Karnes JH; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA.
  • Weiss ST; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA.
  • Wang TJ; Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, 17822, USA.
  • Stein CM; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA.
  • Denny JC; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Roden DM; Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Nat Commun ; 9(1): 3522, 2018 08 30.
Article in En | MEDLINE | ID: mdl-30166544
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Full text: 1 Database: MEDLINE Main subject: Biomarkers / Genome-Wide Association Study / Electronic Health Records Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Nat Commun Year: 2018 Type: Article Affiliation country: United States
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Biomarkers / Genome-Wide Association Study / Electronic Health Records Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Nat Commun Year: 2018 Type: Article Affiliation country: United States