Identification of Effective Dimeric Gramicidin-D Peptide as Antimicrobial Therapeutics over Drug Resistance: In-Silico Approach.

Pavithrra, G; Rajasekaran, R

Pavithrra, G; Rajasekaran, R.

Affiliation

Pavithrra G; Bioinformatics Lab, Department of Biotechnology, School of Biosciences and Technology, VIT (Deemed to be University), Vellore, 632014, India.
Rajasekaran R; Bioinformatics Lab, Department of Biotechnology, School of Biosciences and Technology, VIT (Deemed to be University), Vellore, 632014, India. rrajasekaran@vit.ac.in.

Interdiscip Sci ; 11(4): 575-583, 2019 Dec.

Article in En | MEDLINE | ID: mdl-30182355

Subject(s)

Anti-Infective Agents/chemistry; Drug Resistance, Microbial; Gramicidin/chemistry; Anti-Infective Agents/pharmacology; Chemistry, Pharmaceutical/methods; Computer Simulation; Dimerization; Drug Design; Drug Discovery; Gramicidin/pharmacology; Markov Chains; Microbial Sensitivity Tests; Protein Structure, Secondary; Software; Thermodynamics

Key words

Antibiotic resistance; Antimicrobial peptide (AMP); Gramicidin; Structural stability and functional activity; g-AB; g-AC; g-BC

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Drug Resistance, Microbial / Gramicidin / Anti-Infective Agents Type of study: Diagnostic_studies / Health_economic_evaluation / Prognostic_studies Language: En Journal: Interdiscip Sci Year: 2019 Type: Article Affiliation country: India

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